2-[(Naphthalen-1-yl)methylidene]butanedioic acid → 3-[(Naphthalen-1-yl)methylidene]oxolane-2,5-dione

Participants

Reaction Conditions

Reaction Steps

A mixture of 24.5 g of 2-(1-naphthylmethylene)succinic acid in 260 ml of acetic anhydride was heated at 60° C. for 1 hour. The reaction mixture was concentrated under reduced pressure, and to the residue was added a mixture of benzene and hexane (1:1 by volume), and precipitated crystals were collected by filtration to obtain 16.0 g of 2-(1-naphthylmethylene)succinic anhydride as orange yellow crystals.

Provenance & Evidence