反应详情

using 3-(4-chloro-2-fluoro-5-isopropoxyphenyl)-1,5,6,7-tetrahydro-2H-cyclopenta[d]pyrimidine-2,4(3H)dione in sodium methylate/methanol with methyl iodide there is obtained 3-(4-chloro-2-fluoro-5-isopropoxyphenyl)-1,5,6,7-tetrahydro-1-methyl-2H-cyclopenta[d]-pyrimidine-2,4(3H)-dione, m.p. 125°-127° C.;