HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-1H-indole-2-carbonyl chloride → N-{4-[4-amino-7-({3-[[3-(dimethylamino)propyl](methyl)amino]propanoyl}amino)thieno[3,2-c]pyridin-3-yl]-2-methoxyphenyl}-1-methyl-1H-indole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-1H-indole-2-carbonyl chloride | HCID 12303314 | — |
| Reactant | N-[4-Amino-3-(4-amino-3-methoxyphenyl)-thieno[3,2-c]pyridin-7-yl]-3-[(3-dimethylamino-propyl)methylamino]propionamide | HCID 18451405 | — |
| Product | N-{4-[4-amino-7-({3-[[3-(dimethylamino)propyl](methyl)amino]propanoyl}amino)thieno[3,2-c]pyridin-3-yl]-2-methoxyphenyl}-1-methyl-1H-indole-2-carboxamide | HCID 18451113 | — |
Reaction Steps
The title compound was prepared using 1-methyl-1H-indole-2-carbonyl chloride, N-[4-Amino-3-(4-amino-3-methoxyphenyl)-thieno[3,2-c]pyridin-7-yl]-3-[(3-dimethylamino-propyl)methylamino]propionamide, and the procedure described in General Procedure F. m/z (M+H)+ 614.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07737160B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-9d030d2f04c74d2daa36ee414969e380 |
| Source note | uspto-grants-2010_06 |