1H-1,2,4-Triazole → 3-[(1H-1,2,4-triazol-1-yl)methyl]-1,2-benzisoxazole

HRID 1723074Notes

Reaction equation

HRID 1723074 reaction equation
Br[CH2:2][C:3]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][N:4]=1.[NH:12]1[CH:16]=[N:15][CH:14]=[N:13]1>>[N:12]1([CH2:2][C:3]2[C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=3[O:5][N:4]=2)[CH:16]=[N:15][CH:14]=[N:13]1

Participants

3

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 34991891,2-Benzisoxazole, 3-(bromomethyl)-

Product 1

HCID 145750043-[(1H-1,2,4-triazol-1-yl)methyl]-1,2-benzisoxazole

Procedure

Similarly condensation of 3-bromomethyl-1,2-benzisoxazole with 1,2,4-triazole affords 3-[(1H-1,2,4-triazol-1-yl)methyl]-1,2-benzisoxazole, m.p. 102°-104° C.

Sources & evidence

ORD record
ord-c06f4bd664c8492f92240a0963bbb978
Source dataset
uspto-grants-1989_08
Patent number
US04859691

Reaction notes

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