反应详情

(a-1) To a stirred and cooled (water-bath) mixture of 48.5 parts of (4-amino-3-nitrophenyl)phenylmethanone and 320 parts of methanol were added portionwise 11.4 parts of sodium tetrahydroborate. Upon completion, stirring was continued for 15 minutes at room temperature. 100 Parts of water were added and the methanol was evaporated. The precipitated product was filtered off, washed with water, dried, filtered and crystallized twice from a moisture of methanol and water, yielding 19.6 parts of 4-amino-3-nitro-α-phenylbenzenemethanol; mp. 125° C. (int. 124).

1. temperaturecooled
2. stirringUpon completion, stirring
3. customthe methanol was evaporated
4. filtrationThe precipitated product was filtered off
5. washwashed with water
6. customdried
7. filtrationfiltered
8. customcrystallized twice from a moisture of methanol and water