m-Chloroperbenzoic acid → HCID 14555181, compound

Participants

Reaction Conditions

Reaction Steps

To a methylene chloride solution containing 2.09 g (10 mmol) of 2-methylthio-N-(2,6-dimethylphenyl)acetamide was added, in portions over 30 min with stirring at 5° C., 2.16 g (10 mmol) of m-chloroperbenzoic acid (80% solution). The reaction mixture was kept at 5° C. for an additional 1.25 hr. The precipitate formed was filtered and washed twice with methylene chloride. The filtrate and washings were combined, washed once with saturated aqueous sodium bicarbonate solution, dried over anhydrous sodium sulfate, and evaporated under reduced pressure. The residue was recrystallized from ethyl acetate to afford white crystalline compound (88% yield), mp 112°-114° C.

Provenance & Evidence