HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 19769834, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Cyclopentylmethyl 4-methylbenzene-1-sulfonate | HCID 12568544 | — |
| Reactant | HCID 19769831 | HCID 19769831 | — |
| Product | HCID 19769834 | HCID 19769834 | 48.9% |
Reaction Steps
Using the procedures described above for Intermediate 10, 1,2,3,9-tetrahydro-3-[[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]-4H-carbazol-4-one (500 mg) was treated with sodium hydride (73% dispersion in oil; 38 mg) and was then stirred with cyclopentanemethanol (p-toluenesulphonate) (292 mg) for 24 h. Work up and FCC was described above gave the title compound (283 mg), p.p. 177°-179°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04859662 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-af1a962c39e14f0ea98b36e366cbdcfd |
| Source note | uspto-grants-1989_08 |