2,6-Octadiene, 1-bromo-3,7-dimethyl-, (2E)- → 2-Geranylthio-3-phenyl-4(3H)-quinazolinone

HRID 1723329Notes

Reaction equation

HRID 1723329 reaction equation
[SH:1][C:2]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:10](=[O:18])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[CH2:19](Br)/[CH:20]=[C:21](/[CH2:23][CH2:24][CH:25]=[C:26]([CH3:28])[CH3:27])\[CH3:22]>>[CH2:19]([S:1][C:2]1[N:11]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:10](=[O:18])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1)/[CH:20]=[C:21](/[CH2:23][CH2:24][CH:25]=[C:26]([CH3:28])[CH3:27])\[CH3:22]

Participants

3

Reactant 2

HCID 53658672,6-Octadiene, 1-bromo-3,7-dimethyl-, (2E)-HCID 178515047HCID 178515047, compound

Product 1

HCID 145751542-Geranylthio-3-phenyl-4(3H)-quinazolinoneYield 57.6%

Procedure

The title compound was prepared in a yield of 57.6%. using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3-isobutyl-2-mercapto-4(3H)-quinazolinone and geranyl bromide in place of 2-chloromethylpyridine hydrochloride.

Sources & evidence

ORD record
ord-1f7002831b024205ad87e8254cf54e01
Source dataset
uspto-grants-1989_08
Patent number
US04861780

Reaction notes

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