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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1723332Generated: November 1, 2026

2-(Bromomethyl)thiophene → 3-Phenyl-2-(2-thienylmethylthio)-4(3H)-quinazolinone

https://huagongshe.com/reaction/1723332

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)thiopheneHCID 11829978—
ReactantHCID 178515047HCID 178515047—
Product3-Phenyl-2-(2-thienylmethylthio)-4(3H)-quinazolinoneHCID 1457515737.4%

Reaction Steps

The title compound was prepared in a yield of 37.4%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3-isobutyl-2-mercapto-4(3H)-quinazolinone and 2bromomethylthiophene in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04861780
Source datasetuspto-grants-1989_08
ORD IDord-5661b0e66b904aba9b6a3bfcb21e017d
Source noteuspto-grants-1989_08