4-(Chloromethyl)pyridinium chloride → HCID 14575173, compound

HRID 1723336Notes

Reaction equation

HRID 1723336 reaction equation
[SH:1][C:2]1[N:11]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)[C:10](=[O:19])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.Cl.Cl[CH2:22][C:23]1[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=1>>[CH3:18][C:15]1[CH:14]=[CH:13][C:12]([N:11]2[C:10](=[O:19])[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[N:3]=[C:2]2[S:1][CH2:22][C:23]2[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=2)=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 745704-(Chloromethyl)pyridinium chlorideHCID 178426261HCID 178426261, compound

Product 1

HCID 14575173HCID 14575173, compoundYield 60.8%

Procedure

The title compound was prepared in a yield of 60.8%, using 2-mercapto-3-(4-methylphenyl)-4(3H)-quinazolinone in place of 2-mercapto-3-phenyl-4(3H)-quinazolinone and 4-chloromethylpyridine hydrochloride in place of 2-chloromethyl4-methylpyridine hydrochloride.

Sources & evidence

ORD record
ord-a642c8ea614e49b09e0cc4bceb28a8dc
Source dataset
uspto-grants-1989_08
Patent number
US04861780

Reaction notes

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