4-(Chloromethyl)pyridinium chloride → HCID 136016636, compound

HRID 1723337Notes

Reaction equation

HRID 1723337 reaction equation
[SH:1][C:2]1[NH:11][C:10](=[O:12])[C:9]2[C:4](=[C:5]([CH3:13])[CH:6]=[CH:7][CH:8]=2)[N:3]=1.Cl.Cl[CH2:16][C:17]1[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=1>>[CH3:13][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:4]=1[N:3]=[C:2]([S:1][CH2:16][C:17]1[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=1)[NH:11][C:10]2=[O:12]

Participants

3

Reactant 2

HCID 745704-(Chloromethyl)pyridinium chlorideHCID 178423914HCID 178423914, compound

Product 1

HCID 136016636HCID 136016636, compoundYield 44%

Procedure

The title compound was prepared in a yield of 44.0%, using 2-mercapto-8-methyl-4(3H)-quinazolinone in place of 2-mercapto-3-phenyl-4(3H)-quinazolinone and 4-chloromethylpyridine hydrochloride in place of 2-chloromethyl4-methylpyridine hydrochloride.

Sources & evidence

ORD record
ord-1e64c664f0d1494895ffc7d4a98ae79b
Source dataset
uspto-grants-1989_08
Patent number
US04861780

Reaction notes

Loading…