Thionyl Chloride → HCID 20025664, compound

HRID 1723408Notes

Reaction equation

HRID 1723408 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=O)=[CH:5][CH:4]=1.S(Cl)([Cl:22])=O>C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([Cl:22])=[O:19])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 14555669HCID 14555669, compound

Product 1

HCID 20025664HCID 20025664, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To an ice-cold, stirring solution of 3 gm 9(4-methoxyphenyl)nonanoic acid in 10 ml. CH2Cl2 was added dropwise 1.2 ml thionyl chloride. The solution was then allowed to warm up to room temperature. The solvent and excess thionyl chloride were removed in vacuo to give a brown oil, which was used directly in the last step without further purification.

Workup

  1. customThe solvent and excess thionyl chloride were removed in vacuo
  2. customto give a brown oil, which
  3. customwas used directly in the last step without further purification

Sources & evidence

ORD record
ord-aab12e7043bc497c8d1a1db10757b098
Source dataset
uspto-grants-1989_08
Patent number
US04861798

Reaction notes

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