HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 19908223, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Product | HCID 19908223 | HCID 19908223 | — |
Reaction Steps
Compound (I) wherein R2 is derived from compound (III) wherein n is 1, m is 2 and Q is hydrogen is formed on reacting benzylamine rather than monomethylamine with compound 16 in Scheme III. Proceeding as in Scheme III, 8-benzyl-3,8-diazabicyclo[4.1.1]octane is formed which is coupled with compound (II) and then debenzylated by catalytic hydrogenation, as before.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04861779 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-5875b192e0034d0d85cdfa0074e51e19 |
| Source note | uspto-grants-1989_08 |