Hydrochloric Acid → (E)-2-[2-(4-Diethylaminobutoxyphenyl)ethenyl]benzothiazole

Participants

Reaction Steps

The procedure of Example 38 was followed starting with (H) of Example 38 (3.0 g, 8.7 mmol) and using diethylamine in place of dipropylamine to produce 1.2 g (31% yield) of the title compound as the HCl salt, mp 205°-207° C. IR(KBr): 3400, 1605 cm-1. MS: 381(MH+). 1H NMR (CD3OD): δ 8.14-7.04 (m, 10H), 4.14 (t, J=5.2 Hz, 2H), 3.25 (m, 6H), 1.98 (m, 4H), 1.34 (m, 6H).

Provenance & Evidence