HCID 24127680, compound → HCID 54505073, compound

HRID 1723550Notes

Reaction equation

HRID 1723550 reaction equation
[CH3:1][N:2]([CH3:15])[C:3](=[C:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[NH:7][C:6]1=[O:14])[CH3:4]>CCCCCC>[CH3:5][C:13]1[CH:12]=[C:11]([N:7]2[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[C:5](=[C:3]([N:2]([CH3:1])[CH3:15])[CH3:4])[C:6]2=[O:14])[CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 1

HCID 24127680HCID 24127680, compound

Product 1

HCID 54505073HCID 54505073, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Using a reaction time of 18 hours at reflux and crystallizing the product from hexane after chromatography, 3-(1-dimethylaminoethylidene)-2(1H,3H)-indolone (4.06 g, 20 mmoles) was converted to present title product, 0.45 g, m.p. 96°-99°.

Workup

  1. customa reaction time of 18 hours
  2. temperatureat reflux

Sources & evidence

ORD record
ord-2ded21f10f8a432d9379e86cdd41ddbd
Source dataset
uspto-grants-1989_08
Patent number
US04861880

Reaction notes

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