HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → 1-(4-methoxyphenyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | 4-Bromoanisole | HCID 7730 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Product | 1-(4-methoxyphenyl)-1H-indole | HCID 775715 | — |
Reaction Steps
By the method of Preparation C43, p-bromoanisole (140 g, 0.75 mole), indole (60 g, 0.51 mole), K2CO3 (75 g, 0.54 mole) and Cu2Br2 (28 g, 0.1 mole) were converted to title product, purified by distillation, rather than chromatography, 67.7 g, b.p. 150-160/0.4-0.5 mm, which crystallized on storage in the refrigerator, m.p. 52°-54° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04861880 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-1211cc70f7b34f70a2a5c73b34c2c349 |
| Source note | uspto-grants-1989_08 |