HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → N-(3-Fluorophenyl)-alpha-chloroacetanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 3-fluoro-N-phenylaniline | HCID 2774466 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | N-(3-Fluorophenyl)-alpha-chloroacetanilide | HCID 13339453 | — |
Reaction Steps
N-(3-Fluorophenyl)aniline (7.02 g, 0.0375 mole) and chloroacetyl chloride (3.3 ml, 0.0412 mole) were refluxed in benzene (50 ml) for 3 hours, then evaporated in vacuo to solids and the solids triturated with pentane and ether to yield purified title product, 8.69 g, m.p. 115°-117°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04861880 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-18c3d91b999e45a492b9fdb272a9cead |
| Source note | uspto-grants-1989_08 |