HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 1-(4-Methoxyphenyl)-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 1-(4-methoxyphenyl)-1H-indole | HCID 775715 | — |
| Product | 1-(4-Methoxyphenyl)-1,3-dihydro-2H-indol-2-one | HCID 13339544 | — |
Reaction Steps
Omitting the final chromatography, but triturating the crude product three times with ether, 1-(4-methoxyphenyl)indole (18.1 g, 81 mmoles) was converted to title product, 12.0 g, m.p. 115°-117° C., pnmr/CDCl3 /TMS/delta: 3.65 (s, 2H), 3.8 (s, 3H), 6.6-7.4 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04861880 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-372c916f6f7345ad83160bac72c0ffb5 |
| Source note | uspto-grants-1989_08 |