HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → Ethyl 2-amidino-2-(cyclopropyloxyimino)acetate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Ethyl 3-ethoxy-3-imino-2-(cyclopropyloxyimino)propionate | HCID 54045971 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ethyl 2-amidino-2-(cyclopropyloxyimino)acetate hydrochloride | HCID 73867361 | 90.8% |
Reaction Steps
A mixture of ethyl 3-ethoxy-3-imino-2-(cyclopropyloxyimino)propionate (syn isomer)(9.6 g) and ammonium chloride (3.27 g) in methanol (70 ml) was stirred at ambient temperature for 3 days. The mixture was concentrated in vacuo and triturated with diethyl ether to give crude ethyl 2-amidino-2-(cyclopropyloxyimino)acetate hydrochloride (syn isomer) (9.00 g) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04861769 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-9ab38cc66dea4ca9bd618b8351082f50 |
| Source note | uspto-grants-1989_08 |