HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-Hydroxybutyrate → ethyl (S)-4-azido-3-hydroxybutyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-Hydroxybutyrate | HCID 62572 | — |
| Reactant | Ethyl 4-azido-3-hydroxybutyrate | HCID 14685344 | — |
| Product | ethyl (S)-4-azido-3-hydroxybutyrate | HCID 10888398 | 80.2% |
Reaction Steps
Instead of ethyl 3-hydroxybutyrate used in Example 1, ethyl 4-azido-3-hydroxybutyrate was used. The reaction was carried out for 1 hour and ethyl (S)-4-azido-3-hydroxybutyrate (80.2% e.e) was obtained at 83.5% conversion.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07485452B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-db7f65637b054d018429f55febfd6198 |
| Source note | uspto-grants-2009_02 |