Pyridine, 1,2,3,6-tetrahydro-4-[4-(trifluoromethyl)phenyl]- → HCID 11540504, compound

HRID 1723645Notes

Reaction equation

HRID 1723645 reaction equation
[CH3:1][S:2]([C:5]1[CH:6]=[CH:7][C:8]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[C:9]([CH:13]=1)[C:10]([OH:12])=O)(=[O:4])=[O:3].[F:20][C:21]([F:35])([F:34])[C:22]1[CH:27]=[CH:26][C:25]([C:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH:33]=2)=[CH:24][CH:23]=1>>[CH3:1][S:2]([C:5]1[CH:6]=[CH:7][C:8]([N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[C:9]([C:10]([N:31]2[CH2:30][CH:29]=[C:28]([C:25]3[CH:26]=[CH:27][C:22]([C:21]([F:20])([F:34])[F:35])=[CH:23][CH:24]=3)[CH2:33][CH2:32]2)=[O:12])[CH:13]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 12440708Pyridine, 1,2,3,6-tetrahydro-4-[4-(trifluoromethyl)phenyl]-HCID 211003195-(Methanesulfonyl)-2-(morpholin-4-yl)benzoic acid

Product 1

HCID 11540504HCID 11540504, compound

Procedure

According to the procedure described for the synthesis of example 4, step f, the title compound has been synthesized from 5-Methanesulfonyl-2-morpholin-4-yl-benzoic acid and 4-(4-Trifluoromethyl-phenyl)-1,2,3,6-tetrahydro-pyridine. MS (m/e): 495.4 (MH+, 100%)

Workup

  1. customdescribed for the synthesis of example 4, step f

Sources & evidence

ORD record
ord-ccabd61116b549dfa48cefeceb145a91
Source dataset
uspto-grants-2009_02
Patent number
US07485637B2

Reaction notes

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