4-(4-Chlorophenyl)-1,2,3,6-tetrahydropyridinium chloride → HCID 11632334, compound

HRID 1723651Notes

Reaction equation

HRID 1723651 reaction equation
[C:1]([C:3]1[CH:4]=[CH:5][C:6]([O:12][CH:13]([CH3:15])[CH3:14])=[C:7]([CH:11]=1)[C:8]([OH:10])=O)#[N:2].Cl.[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH:29]=2)=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH2:29][CH2:28][N:27]([C:8]([C:7]3[CH:11]=[C:3]([CH:4]=[CH:5][C:6]=3[O:12][CH:13]([CH3:15])[CH3:14])[C:1]#[N:2])=[O:10])[CH2:26][CH:25]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 27236124-(4-Chlorophenyl)-1,2,3,6-tetrahydropyridinium chlorideHCID 211002975-Cyano-2-isopropoxybenzoic acid

Product 1

HCID 11632334HCID 11632334, compound

Procedure

According to the procedure described for the synthesis of example 4, step f, the title compound has been synthesized from 5-cyano-2-isopropoxy-benzoic acid (CAS: 845616-14-0) and 4-(4-chloro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride (commercial). MS (m/e): 381.1 (MH+, 100%).

Workup

  1. customdescribed for the synthesis of example 4, step f

Sources & evidence

ORD record
ord-19904cf2407c4ab583ea37516f0e08d1
Source dataset
uspto-grants-2009_02
Patent number
US07485637B2

Reaction notes

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