4-(4-Chlorophenyl)-1,2,3,6-tetrahydropyridinium chloride → HCID 11590406, compound

HRID 1723652Notes

Reaction equation

HRID 1723652 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[CH:14]=[CH:13][C:12]([S:15]([CH3:18])(=[O:17])=[O:16])=[CH:11][C:7]=2[C:8]([OH:10])=O)[CH2:3][CH2:2]1.Cl.[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH:32]=2)=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]2[CH2:32][CH2:31][N:30]([C:8]([C:7]3[CH:11]=[C:12]([S:15]([CH3:18])(=[O:17])=[O:16])[CH:13]=[CH:14][C:6]=3[O:5][CH2:4][CH:1]3[CH2:2][CH2:3]3)=[O:10])[CH2:29][CH:28]=2)=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 27236124-(4-Chlorophenyl)-1,2,3,6-tetrahydropyridinium chlorideHCID 211002282-Cyclopropylmethoxy-5-methanesulfonyl-benzoic acid

Product 1

HCID 11590406HCID 11590406, compound

Procedure

According to the procedure described for the synthesis of example 4, step f, the title compound has been synthesized from 2-cyclopropylmethoxy-5-methanesulfonyl-benzoic acid (CAS: 845616-03-7) and 4-(4-chloro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride (commercial). MS (m/e): 446.0 (MH+, 100%).

Workup

  1. customdescribed for the synthesis of example 4, step f

Sources & evidence

ORD record
ord-c02e75907e344895b83643a485925b07
Source dataset
uspto-grants-2009_02
Patent number
US07485637B2

Reaction notes

Loading…