Ammonium formate → HCID 57559224, compound

Participants

Reaction Steps

To a solution of the product of Step 9 (2 g, 0.06 mmol) in methanol was added excess ammonium formate and 10% Pd/C. The reaction mixture was heated under reflux overnight. After filtering, the solution was evaporated and residue was purified on silica gel (10% methanol/chloroform) to obtain the title product (800 mg). 1H NMR (400 MHz, CDCl3) δ 5.25 (1H,s), 4.7 (1H, m), 3.45 (1H, m), 3.25 (1H, m), 3.04 (m) 2.9 (1H, m), 2.5 (6H, m), 1.80 (4H, m), 1.45 (9H, s). MS m/z 284 (MH+).

Provenance & Evidence