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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1723933Generated: October 30, 2026

Cyclohexanone → Methyl 3-cyclohexyl-1H-indole-6-carboxylate

https://huagongshe.com/reaction/1723933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanoneHCID 7967—
Reactant1H-indole-6-carboxylic acidHCID 595230—
Reactant3-(Cyclohex-1-en-1-yl)-1H-indole-6-carboxylic acidHCID 11184077—
ProductMethyl 3-cyclohexyl-1H-indole-6-carboxylateHCID 11230631—

Reaction Steps

Condensation of 1H-indole-6-carboxylic acid with cyclohexanone can generate 3-cyclohexenyl-1H-indole-6-carboxylic acid. This indole ester can be subjected to sequential reduction and esterification to provide methyl 3-cyclohexanyl-1H-indole-6-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07485633B2
Source datasetuspto-grants-2009_02
ORD IDord-0d761c86fd294dc1916d3012270e947a
Source noteuspto-grants-2009_02