HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-(Trifluoromethyl)phenyl)ethan-1-one → 5-chloromethyl-1-methyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-(Trifluoromethyl)phenyl)ethan-1-one | HCID 69731 | — |
| Reactant | 5-Chloromethyl-1-methyl-3-(3,4,5-trimethoxy-phenyl)pyrazole | HCID 18408486 | — |
| Product | 5-chloromethyl-1-methyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole | HCID 21082224 | — |
Reaction Steps
5-chloromethyl-1-methyl-3-(4-trifluoromethyl-phenyl)-1H-pyrazole was prepared in analogy to the preparation of 5-chloromethyl-1-methyl-3-(3,4,5-trimethoxy-phenyl)-1H-pyrazole described by Kodama et al. (U.S. Pat. No. 6,472,386), but starting from 4-trifluoromethylacetophenone instead of 3′4′5′-trimethoxyacetophenone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07485652B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-85bfbff89cb743e08cc7267474f48539 |
| Source note | uspto-grants-2009_02 |