Ethyl chloroformate → Benzamide

HRID 1724095Notes

Reaction equation

HRID 1724095 reaction equation
ClC(OCC)=O.N[C:8]1[CH:17]=[CH:16][C:11]([C:12](OC)=[O:13])=[CH:10][CH:9]=1.COC(=O)CC1C=CC([NH2:28])=CC=1>>[C:12]([NH2:28])(=[O:13])[C:11]1[CH:16]=[CH:17][CH:8]=[CH:9][CH:10]=1

Participants

4

Reactant 3

HCID 10928Ethyl chloroformateHCID 12082Methyl 4-aminobenzoateHCID 2761030Methyl 2-(4-aminophenyl)acetate

Product 1

HCID 2331Benzamide

Procedure

Converting 3,4-dialkoxy benzoic acid to anhydride by adding ethyl chloroformate thereto, and reacting the anhydride with methyl 4-aminobenzoate or 4-aminophenyl acetic acid methylester, to produce a benzamide compound;

Sources & evidence

ORD record
ord-1ca06b930cea4bb7b1318cecd70022af
Source dataset
uspto-grants-2009_02
Patent number
US07485750B2

Reaction notes

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