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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 172412Generated: October 26, 2026

Hydrochloric Acid → 1-(2-Oxo-2-{4-[3-(trifluoromethyl)benzyl]piperazin-1-yl}ethyl)-3,3-diphenylpiperidin-2-one

https://huagongshe.com/reaction/172412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-(3-(Trifluoromethyl)benzyl)piperazineHCID 2060855—
Reactant2-(2-Oxo-3,3-diphenylpiperidin-1-yl)acetic acidHCID 67359280—
Product1-(2-Oxo-2-{4-[3-(trifluoromethyl)benzyl]piperazin-1-yl}ethyl)-3,3-diphenylpiperidin-2-oneHCID 57400236—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-a3714e67682749848fdd4f1e7889be32
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)