6-chloro-N-(3-methoxybenzyl)nicotinamide → N-(3-Methoxybenzyl)-6-[5-(thiophen-3-ylcarbonylamino)-2-methyl-phenyl]-nicotinamide

HRID 172434Notes

Reaction equation

HRID 172434 reaction equation
[CH3:20][c:21]1[c:22]([B:35]2[O:36][C:37]([CH3:38])([CH3:39])[C:40]([CH3:41])([CH3:42])[O:43]2)[cH:23][c:24]([NH:27][C:28](=[O:29])[c:30]2[cH:31][s:32][cH:33][cH:34]2)[cH:25][cH:26]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][c:10]2[cH:11][c:12]([O:16][CH3:17])[cH:13][cH:14][cH:15]2)[cH:18][cH:19]1>>[c:2]1(-[c:22]2[c:21]([CH3:20])[cH:26][cH:25][c:24]([NH:27][C:28](=[O:29])[c:30]3[cH:31][s:32][cH:33][cH:34]3)[cH:23]2)[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][c:10]2[cH:11][c:12]([O:16][CH3:17])[cH:13][cH:14][cH:15]2)[cH:18][cH:19]1

Participants

3

Reactant 2

HCID 94957946-chloro-N-(3-methoxybenzyl)nicotinamideHCID 21914662N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-thiophenecarboxamide

Product 1

HCID 21914660N-(3-Methoxybenzyl)-6-[5-(thiophen-3-ylcarbonylamino)-2-methyl-phenyl]-nicotinamide

Sources & evidence

ORD record
ord-7017733525bd48d9be86041206331e64
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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