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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 172441Generated: October 31, 2026

Tetrahydrofuran → 2,2,2-Trifluoro-N-{2-methyl-5-[(trimethylsilyl)ethynyl]phenyl}acetamide

https://huagongshe.com/reaction/172441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantN-(5-bromo-2-methylphenyl)-2,2,2-trifluoroacetamideHCID 22637059—
Product2,2,2-Trifluoro-N-{2-methyl-5-[(trimethylsilyl)ethynyl]phenyl}acetamideHCID 59511418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-99abc3352c9448158749d613c272242d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)