HCID 9799644, compound → HCID 9842545, compound

Participants

Reaction Steps

Adam's catalyst (0.045 g) was added to a solution of 6-chloro-4′,7-diacetoxyisoflavone (0.25 g, 0.7 mmol) in ethyl acetate (30 ml) and the mixture was stirred at room temperature under a hydrogen atmosphere for 24 h. The catalyst was removed by filtration through Celite and the resulting filtrate was evaporated in vacuo. The residue was recrystallised from ethanol to yield 6-chloro-4′,7-diacetoxyisoflavan4-one (0.15 g, 60%) as colourless plates. 1H NMR (CDCl3): δ 2.29 (s, 3H, OCOCH3), 2.37 (s, 3H, OCOCH3), 3.98 (dd, 1H, J 6.0 Hz, 7.5 Hz, H3), 4.68 (m, 2H, H2), 6.87 (s, 1H, H8), 7.07 (d, 2H, J 8.6 Hz, ArH), 7.27 (d, 2H, J 8.6 Hz, ArH), 8.01 (s, 1H, H5).

Provenance & Evidence