HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylmethane sulfonyl chloride → C-Cyclohexyl-N-{4-[4-(3-dimethylamino-phenyl)-piperazin-1-yl]-butyl}-methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylmethane sulfonyl chloride | HCID 3871475 | — |
| Reactant | {3-[4-(4-Amino-butyl)-piperazin-1-yl]-phenyl}-dimethyl-amine | HCID 68824299 | — |
| Product | C-Cyclohexyl-N-{4-[4-(3-dimethylamino-phenyl)-piperazin-1-yl]-butyl}-methanesulfonamide | HCID 10094582 | — |
Reaction Steps
Reaction of {3-[4-(4-amino-butyl)-piperazin-1-yl]-phenyl}-dimethyl-amine and cyclohexyl-methanesulfonyl chloride as described in Preparation 8 gave desired compound, C-Cyclohexyl-N-{4-[4-(3-dimethylamino-phenyl)-piperazin-1-yl]-butyl}-methanesulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07488731B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-2e8aea0885c64344a372b30233fbc526 |
| Source note | uspto-grants-2009_02 |