Diethyl pyridin-3-ylphosphonate → HCID 23117755, compound

HRID 1724714Notes

Reaction equation

HRID 1724714 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([P:7](=[O:14])([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10])[CH:2]=1.[H][H]>CCO.C(O)(=O)C.[Pt]=O>[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([P:7](=[O:14])([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10])[CH2:2]1

Participants

5

Reactant 2

HCID 10867660Diethyl pyridin-3-ylphosphonateHCID 178418361HCID 178418361, compound

Product 1

HCID 23117755HCID 23117755, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)SolventHCID 18476134Acetic acid ethanolSolvent

Procedure

Diethyl pyridin-3-ylphosphonate was dissolved in EtOH-acetic acid, to which platinum oxide was added, for stirring under 3.4 kgf/cm2 hydrogen for 120 hours, to obtain diethyl piperidin-3-ylphosphonate.

Workup

  1. additionwas added

Sources & evidence

ORD record
ord-669786b164b749bbaf96071957276a71
Source dataset
uspto-grants-2009_02
Patent number
US07488739B2

Reaction notes

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