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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 172495Generated: October 31, 2026

Methanol → 2-(1,1-Difluoroethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-amine

https://huagongshe.com/reaction/172495

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantN-[2-(1,1-Difluoroethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]acetamideHCID 57937359—
Product2-(1,1-Difluoroethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-amineHCID 57937313—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-7031787048a94ecca07f57949b6fcdbf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)