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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1725090Generated: October 25, 2026

3-(Methylamino)-1-(thiophen-2-yl)propan-1-one → (S)-3-(Methylamino)-1-phenylpropan-1-ol

https://huagongshe.com/reaction/1725090

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylamino)-1-(thiophen-2-yl)propan-1-oneHCID 10035873—
Reactant3-(N-Methylamino)-1-(2-thienyl)-1-propanol, (-)-HCID 10095047—
Product(S)-3-(Methylamino)-1-phenylpropan-1-olHCID 7439089—

Reaction Steps

In particular, it opens up the possibility of obtaining enantiomerically pure or enantiomerically enriched (S)-3-methylamino-1-(2-thienyl)-1-propanol in a simple manner starting from 3-methylamino-1-(2-thienyl)-1-propanone. Likewise, enantiomerically pure or enantiomerically enriched (S)-3-methylamino-1-phenyl-1-propanol can be obtained in a simple manner starting from 3-methylamino-1-phenyl-1-propanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07488833B2
Source datasetuspto-grants-2009_02
ORD IDord-9907bd4345f14f92b26fc1cca479a64d
Source noteuspto-grants-2009_02