HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 73023518, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-[(Tert-butoxy)carbonyl]piperidine-2-carboxylic acid | HCID 581831 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 73023518 | HCID 73023518 | — |
Reaction Steps
Boc-DL-Pip-OH (2.29 g, 10 mmol) and benzyl bromide (1.79 ml, 15 mmol) were reacted in DMF (20 ml) in the presence of triethylamine (2.1 ml, 15 mmol) to obtain Boc-DL-Pip-OBzl as an oily product. This product was reacted with 2 N HCl/dioxane (5 eq.) for 3 hours to obtain H-DL-Pip-OBzl-HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07488712B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-aac81c9c572c43c9b0ed1d3d23776be2 |
| Source note | uspto-grants-2009_02 |