1-Deoxy-1-(methylamino)hexitol → HCID 22252042, compound

Participants

Reaction Conditions

Reaction Steps

230 mg of 1-(4-fluorophenyl)-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}phenyl)azetidin-2-one are dissolved in 5 ml of absolute dimethylformamide. 280 mg of 6-methylaminohexane-1,2,3,4,5-pentaol are then added, and the reaction solution is stirred at 50° C. for 2 h. After concentration using a rotary evaporator and oil pump vacuum at 40° C., the residue is purified by preparative HPLC. The product is obtained as an oil. C37H48F2N2O10 (718) MS (ESI): M+

Provenance & Evidence