HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → 5-Bromoimidazo(1,2-a)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 5-Bromoimidazo[1,2-a]pyridine hydrobromide | HCID 17985430 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5-Bromoimidazo(1,2-a)pyridine | HCID 13037241 | — |
Reaction Steps
Add saturated sodium bicarbonate (300 ml) to a suspension of 5-bromoimidazo[1,2-a]pyridine hydrobromide (13.0 g, 46.96 mmol) in ethyl acetate. Separate the organic layer and wash it with saturated sodium bicarbonate, dry over magnesium sulfate, and concentrated under reduced pressure to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491716B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-69f76c679de34c26b490b568dc1b85f2 |
| Source note | uspto-grants-2009_02 |