HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 68762381, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Acetaldehyde, 2,2-dimethoxy- | HCID 162650 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68762381 | HCID 68762381 | — |
Reaction Steps
Dissolve dimethoxyacetaldehyde (97 g, 0.635 mol, 60% in water) and triethylphosphonoacetate (142 g, 0.633 mmol) in 7:1 tetrahydrofuran:water. Add potassium carbonate (100 g, 0.723 mole) and stir for 4 hours at room temperature. Pour the reaction into ethyl acetate (500 ml) and wash with saturated aqueous sodium bicarbonate and saturated aqueous sodium chloride. Concentrate under reduced pressure to provide the desired compound as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491716B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-8ba3dfd820d44971b512f9ec2ef6b842 |
| Source note | uspto-grants-2009_02 |