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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1725444Generated: November 3, 2026

Anthranilic Acid → 5,10-Dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-one

https://huagongshe.com/reaction/1725444

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnthranilic AcidHCID 227—
Reactant1-Fluoro-2-nitrobenzeneHCID 73895—
Product5,10-Dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-oneHCID 20132730.9%

Reaction Steps

2-Fluoronitrobenzene (847 g, 6 mmol) and 2-aminobenzoic acid (274 mg, 2.0 mmol) were reacted according to GP7 to give 130 mg of the title compound (160FE15A).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491715B2
Source datasetuspto-grants-2009_02
ORD IDord-e3c331037ede4b168c9e1b29a882db08
Source noteuspto-grants-2009_02