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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1725455Generated: November 1, 2026

(Pyridin-4-yl)boronic acid → 8-Chloro-11-(pyridin-4-yl)-5h-dibenzo[b,e][1,4]diazepine

https://huagongshe.com/reaction/1725455

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Pyridin-4-yl)boronic acidHCID 2734379—
Reactant8,5-Dichloro-5H-dibenzo[b,e][1,4]diazepineHCID 57485431—
Product8-Chloro-11-(pyridin-4-yl)-5h-dibenzo[b,e][1,4]diazepineHCID 13562068130.4%

Reaction Steps

4 pyridyl-4-boronic acid (14 mg, 0.12 mmol) and 8,5-dichloro-5H-dibenzo[b,e][1,4]diazepine (160FE64) (26 mg, 0.1 mmol) were reacted according GP11 to give 9.3 mg of the title compound (160FE69A). MS (ESI) 306 (MH+). Purity for MH+ (UV/MS) 98/95.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491715B2
Source datasetuspto-grants-2009_02
ORD IDord-b1a24eb2bbf44b18ba4c26b7af8232a4
Source noteuspto-grants-2009_02