化工社化工社 化学情報印刷レポート · 研究参考用
Cyclohexylmethane sulfonyl chloride → C-Cyclohexyl-N-{4-[4-(3-dimethylamino-phenyl)-piperazin-1-yl]-butyl}-methanesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexylmethane sulfonyl chloride | HCID 3871475 | — |
| 反応物 | {3-[4-(4-Amino-butyl)-piperazin-1-yl]-phenyl}-dimethyl-amine | HCID 68824299 | — |
| 生成物 | C-Cyclohexyl-N-{4-[4-(3-dimethylamino-phenyl)-piperazin-1-yl]-butyl}-methanesulfonamide | HCID 10094582 | — |
反応手順
Reaction of {3-[4-(4-amino-butyl)-piperazin-1-yl]-phenyl}-dimethyl-amine and cyclohexyl-methanesulfonyl chloride as described in Preparation 8 gave desired compound, C-Cyclohexyl-N-{4-[4-(3-dimethylamino-phenyl)-piperazin-1-yl]-butyl}-methanesulfonamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07491727B2 |
| 出典データセット | uspto-grants-2009_02 |
| ORD ID | ord-a535f655742f467b859eb056442adf52 |
| 出典メモ | uspto-grants-2009_02 |