Trifluoroacetic acid → HCID 57562536, compound

Participants

Reaction Steps

Trifluoroacetic acid (2.5 mL) was added to a solution tert-butyl (3S,7S)-1-(cyclopropylmethyl)-2-oxo-7-phenylazepan-3-ylcarbamate (144.1 mg, 0.40 mmol) in dichloromethane (5 mL). After 1 h, the mixture was concentrated and aqueous saturated sodium bicarbonate was added. The mixture was extracted with dichloromethane (2×), and the combined organic extracts were dried over magnesium sulfate, filtered, and concentrated to give the title compound (110 mg).

Provenance & Evidence