HCID 57562539, compound → HCID 57562519, compound

Participants

Reaction Steps

10% palladium on carbon (3.04 g) was added to a solution of methyl N-(tert-butoxycarbonyl)-S-(2-nitro-1-phenylethyl)-D-cysteinate (1.00 g, 2.60 mmol) in acetic acid (50 mL). The reaction vessel was evacuated and back-filled with nitrogen (3×), then back-filled with hydrogen (50 psi). After 18 h the mixture was filtered, concentrated, and saturated aqueous sodium carbonate was added. The mixture was extracted with dichloromethane (3×), and the combined organic extracts were dried over magnesium sulfate, filtered, and concentrated to give the title compound (0.73 g). MS 355 (M+1).

Provenance & Evidence