Benzyl 1-(cyclopropylmethyl)-2-oxo-5-phenyl-1,2-dihydropyridin-3-ylcarbamate → 3-Amino-1-(cyclopropylmethyl)-5-phenylpiperidin-2-one

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Reaction Steps

Benzyl 1-(cyclopropylmethyl)-2-oxo-5-phenyl-1,2-dihydropyridin-3-ylcarbamate (0.061 g, 0.163 mmol) and 10% palladium on carbon (0.060 g) were stirred in ethanol (15 ml) for 6 h under hydrogen atmosphere (50 psi). Catalyst was filtered from the solution and solvent removed in vacuo to produce the title compound (0.031 mg). MS 245 (M+1)

Provenance & Evidence