Hydrochloric Acid → HCID 68853630, compound

Participants

Reaction Steps

In an analogous manner to Example 135, step 4, 1-[1-(3′,4′-dichloro-111′-biphenyl-4-yl)-2-piperazin-1-ylethyl]cyclobutanol dihydrochloride was prepared from tert-butyl 4-[2-(3′,4′-dichloro-1,1′-biphenyl-4-yl)-2-(1-hydroxycyclobutyl)ethyl]piperazine-1-carboxylate. MS (ES) m/z 405.3 ([M+H]+); HRMS: calcd for C22H26Cl2N2O.2.00 HCl, 476.0956; found (ESI), 405.1486.

Provenance & Evidence