HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[1-(3-chloro-4-{[2-(trifluoromethyl)benzyl]oxy}phenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride → HCID 86599963, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[1-(3-chloro-4-{[2-(trifluoromethyl)benzyl]oxy}phenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride | HCID 86599408 | — |
| Reactant | HCID 86599964 | HCID 86599964 | — |
| Product | HCID 86599963 | HCID 86599963 | — |
Reaction Steps
In an analogous manner to Example 24, 1-[1-(3-chloro-4-{[2-(trifluoromethyl)benzyl]oxy}phenyl)-2-(4-methylpiperazin-1-yl)ethylcyclohexanol dihydrochloride was prepared from 1-[1-(3-chloro-4-{[2-(trifluoromethyl)benzyl]oxy}phenyl)-2-piperazin-1-ylethyl]cyclohexanol dihydrochloride (See Example 421). MS (ESI) m/z 511; HRMS: calcd for C27H34ClF3N2O2+H+, 511.23336; found (ESI, [M+H]+), 511.2314.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491723B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-d6c92554a4f243fa87f36c754aabf6d5 |
| Source note | uspto-grants-2009_02 |