Diethyl Ether → HCID 20714165, compound

Participants

Reaction Steps

A solution of Example 393A (0.9 g, 5 mmol) in 10 mL of THF was treated with a 1M solution of LAH in THF (10 mL, 10 mmol), stirred at room temperature for 6 hours, cooled to 0° C., and treated with 10 mL of saturated ammonium chloride and 30 mL of diethyl ether. The organic layer was washed with saturated ammonium chloride solution (3×), dried (Na2SO4), filtered, and concentrated to provide the desired product. MS (ESI(+)) m/e 171 (M+H)+.

Provenance & Evidence