HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium formate → 3-(1H-indol-2-yl)-1H-indazol-5-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium formate | HCID 2723923 | — |
| Reactant | 3-(1H-indol-2-yl)-5-phenoxy-1H-indazole | HCID 136342065 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(1H-indol-2-yl)-1H-indazol-5-ol | HCID 136055979 | 89.4% |
Reaction Steps
A solution of 2.54 g of 3-(1H-indol-2-yl)-5-phenoxy-1H-indazole, of 2.83 g of ammonium formate and 2.54 g of palladium-on-charcoal at 10% in 150 ml of ethanol is refluxed for one hour. The catalyst is filtered through paper and rinsed with ethanol. The filtrate is concentrated to dryness to obtain 1.74 g of 3-(1H-indol-2-yl)-1H-indazol-5-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491710B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-54d6543ecafe4281aa0970c7f41132e1 |
| Source note | uspto-grants-2009_02 |