Trifluoroacetic acid → HCID 136055991, compound

Participants

Reaction Steps

39 mg of 3-(1-tert-butoxycarbonyl-1H-pyrrol-2-yl)-5-(methoxyphenyl-phosphinoyloxy)indazole-1-carboxylic acid tert-butyl ester are dissolved in 0.5 ml of dichloromethane and then 0.5 ml of trifluoroacetic acid is added. The solution is stirred at ambient temperature for approximately two hours. The solvent is evaporated off under reduced pressure in a rotary evaporator. The reaction crude is purified by preparative LC/MS to obtain 19 mg of phenylphosphonic acid methyl ester 3-(1H-pyrrol-2-yl)-1H-indazol-5-yl ester as a trifluoroacetate salt.

Provenance & Evidence